秋葵视频

Research Areas

Neurobiology, Neurophysiology, Neurodegeneration, Neurophysiology, Environmental Neuroscience, Microplastics, and Acetaminophen

Education

Ph.D. 鈥� Neurobiology, University of Alabama at Birmingham
B.S. 鈥� Interdisciplinary Studies with a Concentration in Integrative Biology, University of Florida

Publications

1. Mans RA, Kelehear H, Rotschafer S, Ganas C, Uche-Moon B, Call G, Mauersberg CC, Toller J, Diamanduros A. Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon. Front Mol Neurosci. 2025 May 27;18:1563086. doi: 10.3389/fnmol.2025.1563086. PMID: 40496801; PMCID: PMC12149195.
   
2. Moore NS, Mans RA, McCauley MK, Allgood CS, Barksdale KA. Critical Effects on Akt Signaling in Adult Zebrafish Brain Following Alterations in Light Exposure. Cells. 2021 Mar 12;10(3):637. doi: 10.3390/cells10030637. PMID: 33809219; PMCID: PMC8000057.
   
3. Mans RA, Hinton KD, Payne CH, Powers GE, Scheuermann NL, Saint-Jean M. Cholinergic Stimulation of the Adult Zebrafish Brain Induces Phosphorylation of Glycogen Synthase Kinase-3 尾 and Extracellular Signal-Regulated Kinase in the Telencephalon. Front Mol Neurosci. 2019 Apr 16;12:91. doi: 10.3389/fnmol.2019.00091. PMID: 31040768; PMCID: PMC6476920.
   
4. Mans RA, Warmus BA, Smith CC, McMahon LL. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. J Neurophysiol. 2014 Nov 15;112(10):2388-97. doi: 10.1152/jn.00048.2014. Epub 2014 Aug 20. PMID: 25143547; PMCID: PMC4315450.

Funding

Previous Grants

1. Long-term microplastic persistence in neural tissues of Danio rerio (zebrafish). Sigma Xi, The Scientific Research Honor Society.

Research Projects

Micro-and nanoplastic impacts on the central nervous system

We are using pre-clinical animal models and human samples to develop a more comprehensive view of detrimental changes to brain health resulting from daily ingestion of micro- and nanoplastics in food and water. These experiments will yield insights into the progression of cognitive symptoms that may develop in humans over a lifetime of consuming plastic-contaminated food and water.

A 鈥淒ouble-Hit鈥� model of neurodevelopmental risk: Synergistic effects of perinatal inflammation and Acetaminophen on dopaminergic pathways

Acetaminophen (Tylenol) is considered safe for pregnant women and infants as a treatment for inflammatory conditions during illness or proceeding injury. However, the impacts of acetaminophen on brain development in the context of inflammation have not been thoroughly investigated. My lab is working closely with Dr. Joshua Herrington in the Department of Psychology to evaluate preclinical animal models for studying the neurodevelopmental impacts of acetaminophen in the context of inflammation.

News

1. Former student Justin Toller. BS, Biology (2025). Completing MS in Neuroscience at the University of Florida (McKnight Brain Institute)
2. Former student Makenzi Thomas. BS, Biochemistry (2023), McNair Scholar, Amgen Scholar. Completing Ph.D. in Systems, Synthetic and Physical Biology at Rice University
3. Former student Laura Loera-Lopez. BS, Biology and Minor in Neuroscience (2021). Completing Ph.D in Neuroscience at University of Georgia
4. Former student Savannah Myers. BS, Biology (2020). Clinical Research Associate at Perexel (Atlanta, GA)
5. Former student Kyle Hinton. BS, Biology (2019). Research Assistant at Mercer University College of Medicine (Savannah); Formerly at PPD and Thermo Fisher Scientific.

Research Group

Undergraduate Students

• Brendan Uche-Moon
• Salena Jones
• Jay Wasylk

Graduate Students

• Callie Mauersberg (MS)
• Jade Bender (MS)